Andy Roddick has one of the most storied careers at the US Open of all time. The American won the tournament in 2003, was a finalist in 2006, and -including his wins here this year -is a combined 53-12 overall. We take a look back at his ten best matches from Roddick's 13 Opens.
2001 Quarterfinals: Lost to  Lleyton Hewitt 6-7 (5), 6-3, 6-4, 3-6, 6-4
It was Andy’s first legitimate run at a major and he made the most of it, taking one of the favorites to five sets. But Roddick was incensed by an overrule early in the tenth game of the final set and was eventually broken in that game. Hewitt would go on to win the tournament.
2002 Fourth Round: Def. Juan Ignacio Chela 5-7, 6-4, 6-4, 6-4
Containing perhaps one of the most famous points Roddick ever played at the Open, the 20-year-old ran down ball after ball, eventually hitting a down-the-line backhand winner and high-fiving fans in the first row on Louis Armstrong Stadium. The American would lose to Pete Sampras in the next round.
2003 Semifinals: Def.  David Nalbandian 6-7 (4), 3-6, 7-6 (7), 6-1, 6-3
Roddick saved a match point in this contest that could have easily gone the way of the Argentine in straight sets. But after the American grabbed the third set, he lost just four games in the final two sets. Nalbandian, already a finalist at Wimbledon a year before, still has never won a major to this day.
2003 Final: Def.  Juan Carlos Ferrero 6-3, 7-6 (2), 6-3
With the hard work behind him, Roddick took down clay court specialist Ferrero in a three-set final in which the 21-year-old served lights out. Roddick belted three aces to finish off the Spaniard before hopping into the stands to hug his family and entourage, winning his first—and only—Grand Slam.
2004 Second Round: Def. Rafael Nadal 6-0, 6-3, 6-4
Playing an 18-year-old Nadal, Roddick ran through the Spanish teen with incredible serving and a booming forehand. Nadal looked downright overwhelmed by Roddick’s power as the defending champion won the first five games in just 14 minutes. Roddick was eventually stunned in the quarterfinals by Swede Joachim Johansson.
2006 Third Round: Def.  Fernando Verdasco 6-7 (5), 6-3, 6-4, 6-7 (4), 6-2
Roddick played just five five-set matches in 51 career matches at Flushing Meadows (coming into the 2012 tournament), but only won two of them: his 2003 Nalbandian semifinal and this one against Verdasco. The hard-hitting Spanish lefty gave Roddick plenty of trouble, but after blowing the fourth set he finished out the match to face Mikhail Youzhny in the semifinals.
2006 Final: Lost to  Roger Federer 6-2, 4-6, 7-5, 6-1
It was Roddick’s only other final in New York other than his win in 2003, and just one of two times that he would play Federer at the USTA Billie Jean King National Tennis Center. At 5-all in the third, it appeared as though it could go the American’s way, but Federer held with ease and then hit a sizzling backhand pass to earn set points, going up two sets to one and never looking back.
2008 Quarterfinal: Lost to  Novak Djokovic 6-2, 6-3, 3-6, 7-6 (5)
The match that solidified that Roddick had another nemesis in this tennis generation in Djokovic, then a one-time Slam winner from the 2007 Australian Open. Roddick had a break lead and served for the fourth set at 5-3, only to be broken. Djokovic then trotted through the tiebreak.
2009 Third Round: Lost to John Isner 7-6 (3), 6-3, 3-6, 5-7, 7-6 (5)
Perhaps the true changing-of-the-guard match, Isner stunned Roddick in 2009 in a fifth-set tiebreak that went late into the New York night. Isner was ranked just 55th at the time, and Roddick was coming off his epic 2009 Wimbledon final loss to Federer and a solid summer season. Isner called the win “by far” the greatest of his career up to that point.
2011 Fourth Round: Def.  David Ferrer 6-3, 6-4, 3-6, 6-3
Weather and then court issues had pushed these two seeded stars onto Court 13 to contest a fourth-round match, but it was Roddick who weathered the fierce consistency of the Spaniard the best. Roddick entered the match 3-5 lifetime against the higher seed, but conjured up some of his greatest US Open tennis to advance into the quarterfinals, where he lost to Rafael Nadal.